Genome-Wide Expression - CTD-Phosphatase

Genome-wide expression analysis was used to identify genes affected by the FCP1 CTD-phosphatase.

This site supports Kobor, et al., A Novel Protein Phosphatase Required for Dephosphorylation of the CTD and Transcription by RNA polymerase II in Saccharomyces cerevisiae, Mol. Cell, 4:55-62 (1999). The data are presented with previously published data from Holstege, et al. (1998).

Project Goals
Genetic Reagents
Technology, Protocols, and Analysis

Yeast mRNA Population

Transcriptome
Apparent Half-life and Transcriptional Frequency

Genome-Wide Expression Data

• How gene expression depends on components of transcriptional machinery

  CTD-phosphatase
  RNA Polymerase II
  SRB/Mediator Core Complex
  SRB10 CDK Complex
  SWI/SNF Complex
  General Transcription Factors
  SAGA
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• How expression of gene X depends on multiple components of the machinery

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Results and Insights

Summary
Table of Results