The
Reddien
Lab
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Publications
Lab Members
MIT Department of Biology
Whitehead Institute
9 Cambridge Center
Cambridge, MA 02142
(617) 258-9243
Publications
Lapan SW and Reddien PW.
Transcriptome analysis of the planarian eye identifies ovo as a specific regulator of eye regeneration.
Cell Rep
2(2)
, 294-307 (2012).
Wenemoser D, Lapan SW, Wilkinson AW, Bell GW, Reddien PW.
A molecular wound response program associated with regeneration initiation in planarians.
Genes Dev
26(9)
, 988-1002 (2012).
Wagner DE, Ho JJ, and Reddien PW.
Genetic regulators of a pluripotent adult stem cell system in planarians identified by RNAi and clonal analysis.
Cell Stem Cell
10(3)
, 299-311 (2012).
Scimone ML, Srivastava M, Bell GW, and Reddien PW..
A regulatory program for excretory system regeneration in planarians.
Development
138(20)
, 4387-98 (2011).
Lapan SW and Reddien PW.
dlx
and
sp6-9
Control Optic Cup Regeneration in a Prototypic Eye.
PLoS Genet
7(8)
, e1002226 (2011).
Tanaka EM, Reddien PW.
The cellular basis for animal regeneration.
Dev Cell
21(1)
, 172-85 (2011).
Reddien PW.
Constitutive gene expression and the specification of tissue identity in adult planarian biology.
Trends Genet
27(7)
, 277-85 (2011).
Petersen CP and Reddien PW.
Polarized
notum
activation at wounds inhibits Wnt function to promote planarian head regeneration.
Science
332(6031)
, 852-5 (2011).
Wagner DE, Wang IE, and Reddien PW.
Clonogenic neoblasts are pluripotent adult stem cells that underlie planarian regeneration.
Science
332(6031)
, 811-6 (2011).
Gavino MA and Reddien PW.
A
bmp
/
admp
regulatory circuit controls maintenance and regeneration of dorsal-ventral polarity in planarians.
Curr Biol
21(4)
, 294-9 (2011).
Wenemoser D and Reddien PW.
Planarian regeneration involves distinct stem cell responses to wounds and tissue absence.
Dev Biol
344(2)
, 979-91 (2010).
Scimone ML, Meisel J and Reddien PW.
The Mi-2-like
Smed-CHD4
gene is required for stem cell differentiation in the planarian
Schmidtea mediterranea
.
Development
137(8)
, 1231-41 (2010).
Petersen CP and Reddien PW.
Wnt signaling and the polarity of the primary body axis.
Cell
139(6)
, 1056-68 (2009).
Glazer AM, Wilkinson AW, Backer CB, Lapan SW, Gutzman JH, Cheeseman IM and Reddien PW.
The Zn finger protein Iguana impacts Hedgehog signaling by promoting ciliogenesis.
Dev Biol
337(1)
, 148-56 (2010).
Petersen CP and Reddien PW.
A wound-induced Wnt expression program controls planarian regeneration polarity.
Proc Natl Acad Sci U S A
106(40)
, 17061-6 (2009).
Reddien PW, Newmark PA and Sanchez Alvarado A.
Gene nomenclature guidelines for the planarian Schmidtea mediterranea.
Dev Dyn
237(11)
, 3099-101 (2008).
Petersen CP and Reddien PW.
Smed-betacatenin-1
is required for anteroposterior blastema polarity in planarian regeneration.
Science
319(5861)
, 327-30 (2008).
Reddien PW, Bermange AL, Kicza AM and Sanchez Alvarado A.
BMP signaling regulates the dorsal planarian midline and is needed for asymmetric regeneration.
Development
134(22)
, 4043-51 (2007).
Reddien PW, Oviedo NJ, Jennings JR, Jenkin JC and Sanchez Alvarado A.
SMEDWI-2 is a PIWI-like protein that regulates planarian stem cells.
Science
310(5752)
, 1327-30 (2005).
Reddien PW, Bermange AL, Murfitt KJ, Jennings JR and Sanchez Alvarado A.
Identification of genes needed for regeneration, stem cell function, and tissue homeostasis by systematic gene perturbation in planaria.
Dev Cell
8(5)
, 635-49 (2005).
Reddien PW and Sanchez Alvarado A.
Fundamentals of planarian regeneration.
Annu Rev Cell Dev Biol
20
, 725-57 (2004).
Newmark PA, Reddien PW, Cebria F and Sanchez Alvarado A.
Ingestion of bacterially expressed double-stranded RNA inhibits gene expression in planarians.
Proc Natl Acad Sci U S A
100
, 11861-5 (2003).