Steve Rozen

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Steve Rozen works in genomics, human genetics, systems biology, and bioinformatics. He has used high-throughput data and within-species variation to extract information about function in the genomes of mammals and, especially, the human genome. This approach led to major advances in our understanding of mammalian Y chromosomes and the genetics of low sperm count in men.

He is also active in analyzing and interpreting high-dimensional data sets, such as those generated by gene-expression and metabolic profiling. He is interested in mining metabolic-profiling data for biomarkers and for mechanistic insights into differing responses to drugs.

For three years he organized and taught yearly, intensive courses in bioinformatics at Cold Spring Harbor Laboratories (with Lincoln Stein).

Previously, as director of chip informatics at the Whitehead/MIT Center for Genome Research, Steve Rozen managed analysis of gene expression microarray data and high-throughput SNP data. His work has also included building and integrating software to support biological research, notably the widely used Primer3 software.

Before joining Whitehead Institute, he did research on automatic code optimization and software engineering environments, and he developed information systems on Wall Street.

Steve Rozen received a Ph.D. for research on database and information systems from the Computer Science Department at New York University, where he studied with Dennis Shasha.

Last updated 2008-04-30      http://jura.wi.mit.edu/rozen/      rozen@wi.mit.edu