Whole-genome ChIP-chip analysis of Dorsal, Twist and Snail suggests integration of diverse patterning processes in the Drosophila embryo
Study Design
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Acknowledgements
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Data
Raw Data
Raw data files and array designs may be obtained from ArrayExpress under the accession number E-TABM-226 as well.
All median ratios across the genome
The data are also displayed on the Furlong lab web site, together with related data from the co-published article: Thomas Sandmann, Charles Girardot, Marc Brehme, Waraporn Tongprasit, Viktor Stolc, and Eileen E.M. Furlong (2007). "A core transcriptional network for early mesoderm development in Drosophila melanogaster".
All target genes of the Dorsal network
This is a tab-delimited text file of all the 861 high-confidence target genes bound by Dorsal, Twist and Snail (DTS regions) or Twist and Snail (TS regions). The table also contains information on known DV enhancers and target genes, as well as binding motifs and their conservation across the 12 Drosophila species.
All target genes of the Dorsal network - extended list
This is an extended list of target genes (3000 DTS and TS regions), which includes regions bound at lower levels.
Array Design
A set of 11 arrays was designed to cover the entire non-repeat-masked euchromatic regions of Drosophila melanogaster. This was achieved by 446,931 features (60mers) that were spaced on average ~280 bp from each other. 866 control spots (oligos from desert regions, the middle of long exons, Arabidopsis thaliana and repetitive sequences) were added to each array. The array was printed by Agilent Technologies.
Design Files
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