Study Design
Data and Downloads
Acknowledgments
|
Literature Evidence of Autoregulation
Table. Known autoregulation in mammalian transcription factors.
Factor |
Symbol |
First Author |
Year |
Species |
Tissue |
P53 |
TP53 |
Benoit |
2000 |
Human |
Adenocarcinoma |
CEBPA |
CEBPA |
Christy |
1991 |
Mouse |
Adipocytes |
CRY1 |
CRY1 |
Kume |
1999 |
Mouse |
Adipocytes |
LXRA |
NR1H3 |
Ulven |
2004 |
Mouse |
Adipose |
BCL6 |
BCL6 |
Wang |
2002 |
Human |
B-cells |
C-MYC |
MYC |
Martinotti |
1988 |
Human |
B-cells |
PU.1 |
SPI1 |
Okuno |
2005 |
Mouse |
Bone Marrow |
NKX2.5 |
NKX2-5 |
Oka |
1997 |
Mouse |
Cardiocytes |
EGR1 |
EGR1 |
Saadane |
2000 |
Mouse |
Cardiocytes |
c-jun |
JUN |
Angel |
1988 |
Human |
Cell lines |
p50 |
NFKB1 |
Ten |
1992 |
Human |
Cell lines |
p50 |
NFKB1 |
Cogswell |
1993 |
Human |
Cell lines |
P53 |
TP53 |
Hudson |
1995 |
Human |
Cell lines |
RB1 |
RB1 |
Ohtani-Fujita |
1994 |
Human |
Cell lines |
CREM |
CREM |
Molina |
1993 |
Rat |
Cell lines |
CDX1 |
CDX1 |
Beland |
2004 |
Mouse |
Embryonic carcinoma |
GSC |
GSC |
Danilov |
1998 |
Mouse |
Embryonic carcinoma |
RB1 |
RB1 |
Hamel |
1992 |
Mouse |
Embryonic carcinoma |
c-Fos |
FOS |
Sassone-Corsi |
1988 |
Mouse |
Embryonic Fibroblasts |
c-Fos |
FOS |
Konig |
1989 |
Mouse |
Embryonic Fibroblasts |
MYOD1 |
MYOD1 |
Thayer |
1989 |
Mouse |
Embryonic Fibroblasts |
P53 |
TP53 |
Deffie |
1993 |
Mouse |
Embryonic Fibroblasts |
SRF |
SRF |
Spencer |
1996 |
Mouse |
Embryonic Fibroblasts |
E2F2 |
E2F2 |
Sears |
1997 |
Rat |
Embryonic Fibroblasts |
STRA13 |
STRA13 |
Sun |
2000 |
Mouse |
Embryonic Fibroblasts |
RBL1 |
RBL1 |
Zhu |
1995 |
Human |
Embryonic Kidney |
xVENT2B |
xVENT2B |
Henningfeld |
2002 |
Xenopus |
Embryos |
PIT1 |
POU1F1 |
Chen |
1990 |
Mouse |
Epithelial |
HDAC1 |
HDAC1 |
Schuettengruber |
2003 |
Mouse |
Fibroblasts |
OCT1 |
POU2F1 |
Pankratova |
2003 |
Mouse |
Fibroblasts |
N-Myc |
MYCN |
Facchini |
1997 |
Rat |
Fibroblasts |
MYB |
MYB |
Nicolaides |
1991 |
Hampster |
Fibroblasts |
PURA |
PURA |
Muralidharan |
2001 |
Human |
Glial/other |
C-MYC |
MYC |
Kitaura |
1991 |
Human |
HeLa |
ER |
ESR1 |
Castles |
1997 |
Human |
HeLa |
ETS1 |
ETS1 |
Jorcyk |
1991 |
Human |
HeLa |
junD |
JUND |
Berger |
1994 |
Human |
HeLa |
junD |
JUND |
Berger |
1998 |
Human |
HeLa |
p49/p100 |
NFKB2 |
Lombardi |
1995 |
Human |
HeLa |
MITF-M |
MITF |
Saito |
2002 |
Human |
HeLa |
GATA2 |
GATA2 |
Grass |
2003 |
Mouse |
Hematopoeitic |
GATA1 |
GATA1 |
Nishikawa |
2003 |
Zebrafish |
Hematopoeitic |
CEBPA |
CEBPA |
Foka |
2001 |
Human |
Hepatoma |
CEBPB |
CEBPB |
Niehof |
2001 |
Human |
Hepatoma |
KLF4 |
KLF4 |
Mahatan |
1999 |
Monkey |
Kidney |
CEBPA |
CEBPA |
Timchenko |
1995 |
Human |
Liver |
LXRA |
NR1H3 |
Li |
2002 |
Human |
Liver |
FOXA2 |
FOXA2 |
Pani |
1992 |
Mouse |
Liver |
HNF4A |
HNF4A |
Briancon |
2004 |
Mouse |
Liver |
CEBPA |
CEBPA |
Legraverend |
1993 |
Rat |
Liver |
TR |
THRA |
Sadow |
2003 |
Mouse |
Liver/Heart |
ETS1 |
ETS1 |
Oka |
1991 |
Human |
Lymphocyte |
GFI1 |
GFI1 |
Doan |
2004 |
Human |
Lymphocyte |
LXRA |
NR1H3 |
Lafitte |
2001 |
Human |
Lymphocyte |
LXRa |
NR1H3 |
Laffitte |
2001 |
Human |
Macrophage |
OCT4 |
POU5F1 |
Okura-Nakanishi |
2005 |
Mouse |
mES |
SOX2 |
SOX2 |
Catena |
2004 |
Mouse |
mES |
MYOD |
MYOD |
Tapscott |
1991 |
Mouse |
Muscle |
PU.1 |
SPI1 |
Chen |
1995 |
Human |
Myeloid |
HES1 |
HES1 |
Hirata |
2002 |
Mouse |
Myoblasts/Fibroblasts/Neuroblastoma/others |
N-Myc |
MYCN |
Sivak |
1997 |
Human |
Neuroblastoma |
BRN3A |
POU4F1 |
Trieu |
2003 |
Mouse |
Neurons |
PAX6 |
PAX6 |
Yamaguchi |
1997 |
Human |
Ocular |
PAX6 |
PAX6 |
Aota |
2003 |
Mouse |
Ocular |
RUNX2 |
RUNX2 |
Tou |
2003 |
Mouse |
Osteoblasts |
RUNX2 |
RUNX2 |
Drissi |
2000 |
Mouse |
Osteoblasts |
E2F1 |
E2F1 |
Neuman |
1994 |
Human |
Osteogenic Sarcoma |
RB1 |
RB1 |
Shan |
1994 |
Human |
Osteogenic Sarcoma |
CDX2 |
CDX2 |
Xu |
1999 |
Mouse |
Pancreas |
PIT1 |
POU1F1 |
Theill |
1993 |
Rat |
Pituitary |
CREB |
CREB1 |
Meyer |
1993 |
Human |
Placental cells |
AR |
AR |
Grad |
1999 |
Human |
Prostate |
c-jun |
JUN |
Mechta |
1994 |
Human |
Review |
PITX1 |
PITX1 |
Goodyer |
2003 |
Mouse |
Stomodeum/Oral ectoderm |
ETS1 |
ETS1 |
Majerus |
1992 |
Human |
T-cell |
STAT3 |
STAT3 |
Narimatsu |
2001 |
Mouse |
T-cell |
CREB |
CREB1 |
Walker |
1995 |
Rat |
Testicular/Sertoli |
GATA3 |
GATA3 |
Zhou |
2003 |
Human |
Th1/Th2 |
TTF1 |
TITF1 |
Oguchi |
1998 |
Human |
Thyroid |
FRA1 |
FOSL1 |
Casalino |
2003 |
Rat |
Thyroid |
CEBPD |
CEBPD |
Yamada |
1999 |
Mouse |
|
CEBPD |
CEBPD |
Tanabe |
2000 |
Rat |
|
GATA1 |
GATA1 |
Orkin |
1995 |
|
|
cREL |
REL |
Hannink |
1990 |
Chicken |
|
GATA1 |
GATA1 |
Tsai |
1991 |
|
|
HES7 |
HES7 |
Bessho |
2001 |
Mouse |
|
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