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Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells

Mapping Transcription Factor Occupancy in Human Embryonic Stem Cells

Data Oct4 Promoter Occupancy in Human ES Cells
Oct4, Sox2 and Nanog Co-occupy Many Target Genes
ES Cell Transcription Factors Occupy Active and Inactive Genes
Core Transcriptional Regulatory Circuitry in ES Cells
Expanded Transcriptional Regulatory Circuitry
Supplementary Information




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Acknowledgements

We would like to thank Bioinformatics and Research Computing (BaRC) and the Center for Microarray Technolgy (CMT) at the Whitehead Institute for computational and technical support.
We would also like to thank members of the Young lab as well as Chad Cowan and Kevin Eggan for helpful discussions.
L.A.B. was supported by NRSA postdoctoral fellowship F32-CA094664. This work was supported by NHGRI grant HG002668 to D.K.G. and R.A.Y. and NIH grant GM069400 to R.A.Y. T.I.L., D.K.G., and R.A.Y. consult for Agilent Technologies.

 
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